2-chlorobenzoate 1,2-dioxygenase - definizione. Che cos'è 2-chlorobenzoate 1,2-dioxygenase
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Cosa (chi) è 2-chlorobenzoate 1,2-dioxygenase - definizione


2-chlorobenzoate 1,2-dioxygenase         
CLASS OF ENZYMES
EC 1.14.12.13; EC 1.14.12.13); 2-halobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dehalogenating, decarboxylating)
In enzymology, a 2-chlorobenzoate 1,2-dioxygenase () is an enzyme that catalyzes the chemical reaction
Alpha-ketoglutarate-dependent hydroxylases         
  • Common inhibitors of αKG-dependent dioxygenases. They compete against the cosubstrate αKG for binding to the active site Fe(II).
  • Consensus catalytic mechanism of the αKG-dependent dioxygenase superfamily.
  • prolyl hydroxylase isoform 2]] (PHD2), a human αKG-dependent dioxygenase. The Fe(II) is coordinated by two imidazoles and one carboxylate provided by the protein.  Other ligands on iron, which are transiently occupied αKG and O<sub>2</sub>, are omitted for clarity.
CLASS OF ENZYMES
2-oxoglutarate (2OG)-dependent dioxygenases; Alpha-ketoglutarate-dependent hydroxylase; 2-oxoglutarate–dependent dioxygenase; 2-oxoglutarate-dependent dioxygenase
Alpha-ketoglutarate-dependent hydroxylases are a major class of non-heme iron proteins that catalyse a wide range of reactions. These reactions include hydroxylation reactions, demethylations, ring expansions, ring closures, and desaturations.
Hydroquinone 1,2-dioxygenase         
CLASS OF ENZYMES
EC 1.13.11.66; Hydroquinone dioxygenase; Benzene-1,4-diol:oxygen 1,2-oxidoreductase; Benzene-1,4-diol:oxygen 1,2-oxidoreductase (decyclizing)
Hydroquinone 1,2-dioxygenase (, hydroquinone dioxygenase) is an enzyme with systematic name benzene-1,4-diol:oxygen 1,2-oxidoreductase (decyclizing). This enzyme catalyses the following chemical reaction